NFL Picks Against the Spread: Week 10 Games


Before the tenth Sunday of the 2026 regular season kicks off, let’s have some fun by taking a look at the lines for the NFL Week 10 games.

You can CLICK HERE for straight up NFL picks without regard to the spread.

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My overall record this season is 62-71-2, which is slightly ahead of the collective BGN community at 60-73-2. We’re battling to get back to .500.

Here are suggestions when trying to beat the odds.

NFL WEEK 10 GAMES

NEW ENGLAND PATRIOTS at DETROIT LIONS (-2.5): The Lions’ offense has been struggling lately but Green Bay destroyed this Pats defense last week and Detroit could wake up here in this Germany game. PICK: Lions -2.5

MINNESOTA VIKINGS at GREEN BAY PACKERS (-2.5): Is Kirk Cousins going to be sharp in his first game back with the Vikings? Seems to me like there could be an adjustment period. And it’s hard to bet against Jordan Love right now, even while going up against Brian Flores. The Packers aren’t getting swept by Minny this season. PICK: Packers -2.5

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HOUSTON TEXANS (-4.5) at CLEVELAND BROWNS: Feels like a meeting between two teams trending in opposite directions. The Texans are heating up after a slow start. The Browns are cooling off after a fast start. PICK: Texans -4.5

KANSAS CITY CHIEFS (-3.5) at ATLANTA FALCONS: This is a line I’d stay away from because the Falcons are a weird team to figure out on a weekly basis. But since I’m making a pick, I’ll lean with Patrick Mahomes’ side. PICK: Chiefs -3.5

MIAMI DOLPHINS at INDIANAPOLIS COLTS (-3.5): This is admittedly weird reasoning. But there’s just something about how bizarrely the Eagles have handled their backup quarterback situation this year that makes me believe former Philly draft pick Kyle McCord is going to light it up for the Dolphins in this game. That feels like the next logical step in this progression. PICK: Dolphins +3.5

CAROLINA PANTHERS at NEW ORLEANS SAINTS (-1.5): The Panthers are riding a three-game losing streak, two of which were decided by more than one possession. This team isn’t any good. Neither are the Saints … but at least they have a home crowd going for them. PICK: Saints -1.5

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JACKSONVILLE JAGUARS (-10.5) at TENNESSEE TITANS: Would be pretty funny if the Jags followed up making big trade deadline acquisitions by losing to the lowly Titans … while resting their new additions, including Jordan Davis. But the Titans’ outlook is pretty bleak. Can’t take them. PICK: Jaguars -10.5

BUFFALO BILLS (-7.5) at NEW YORK JETS: Probably going to regret putting faith in Geno Smith but the Bills are coming off short rest and it’s a division game. The Jets could conceivably cover in a loss. PICK: Jets +7.5

LOS ANGELES RAMS (-9.5) at ARIZONA CARDINALS: The Rams previously lost to the Cardinals. They’re going to get their get-back here against rookie Carson Beck making his first NFL start. PICK: Rams -9.5

SEATTLE SEAHAWKS (-6.5) at LAS VEGAS RAIDERS: Fernando Mendoza making his first career start against Seattle’s defense is a tough spot for the rook. PICK: Seahawks -6.5

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SAN FRANCISCO 49ers (-4.5) at DALLAS COWBOYS: The 49ers absolutely own the Cowboys. No reason to think things will go differently for Dallas this time around. Brock Purdy has been balling; he should be able to carve up an entirely gettable Cowboys defense. PICK: 49ers -4.5

PITTSBURGH STEELERS at CINCINNATI BENGALS (-3.5): Joe Burrow is cooking right now. That said, the Steelers are not likely to go down without a fight. Pittsburgh, coming off their bye week, covers in a loss. PICK: Steelers +3.5

LOS ANGELES CHARGERS at BALTIMORE RAVENS (-4.5): Am I a sucker for believing the Bolts are going to win a game eventually!? Probably. PICK: Chargers +4.5

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